Prof. Dr.
Kemal
YELEKÇİ
Titles
Start | End | Title | Place |
---|---|---|---|
01 July 2001 | 01 September 2007 | Dean, Faculty of Science and Arts | Kadir Has University |
01 January 2001 | 31 December 2003 | Vice rector | Kadir Has University |
01 September 1998 | 01 July 2001 | Dean, Faculty of Science and Arts | Marmara University |
Career
Start | End | Work | Position |
---|---|---|---|
01 January 1987 | 01 January 1988 | Northwestern University – Department of Medicinal Chemistry | Post-doc reseracher |
01 January 1988 | 31 December 1989 | Ege University, Department of Chemistry | Asst. Prof. |
01 January 1990 | 01 January 2001 | Marmara University, Department of Chemistry | Assoc. Prof. |
01 January 2001 | - | Kadir Has University, Department of Bioinformatics and Genetics | Prof. Dr. |
Education
Education | University | Department | Date |
---|---|---|---|
Ph. D. | University of Ohio | Department of Organic Chemistry | 1987 |
Master's | Çukurova University | Department of Organic Chemistry | 1981 |
B.Sc. | METU | Department of Chemistry | 1979 |
Areas of interest
Computer-aided drug design | Molecular Dynamics and quantum mechanic methods |
Computational chemistry |
Courses
Code | Course Name | Course Location | Semester |
---|---|---|---|
CH-500 | Nuclear Magnetic Spectroscopy & Applications | Marmara University | Spring 1990-91 - Spring 1995-96 - Spring 1999-2000 |
CH-450 | Spectroscopic Identification of Organic Compounds | Marmara University | Spring 2000-01 - Spring 1999-2000 |
PC-157 | History of Science I | Kadir Has University | Fall 2013-14 |
BIO-531 | Essential Cell Biology | Kadir Has University | Fall 2012-13 |
CH-101 | General Chemistry | Kadir Has University | Fall 2013-14, Fall 2012-13 |
BIO-206 | Organic Chemistry II | Kadir Has University | Spring 2014-15 |
BIO-201 | Organic Chemistry I | Kadir Has University | Fall 2014-15 |
BIO-622 | Special Topics in Medicinal Chemistry | Kadir Has University | Spring 2014-15 |
BIO-520 | Organic Chemistry of Drug Design and Drug Action | Kadir Has University | Spring 2014-15 |
BIO-511 | Introduction to Bioinformatics | Kadir Has University | Fall 2014-15 |
Projeler
Start | Start | Project Name | Project Type | Word | Fund Committee |
---|---|---|---|---|---|
27.4.2020 | 27.4.2022 | Kanser tedavisinde kullanılmak üzere histon deasetlaz HDAC6 ve HDAC10 enzimlerine karşı in siliko tarama ve medisinal kimya yaklaşımlarını kullanılarak etkili ve seçimli yeni inhibitörler geliştirmek | Araştırma Projesi | Yürütücü | TÜSEB (Türkiye Sağlık Enstitüleri Başkanlığı) |
Mart 2020 | Mart 2022 | Molecular modeling, synthesis, and potential anticancer activity of heteroaryl sulfanyl acetamide derivatives through apoptosis, angiogenesis and mPGES-1enzyme (Microsomal prostaglandin E2 synthase1) inhibiton | Araştırma Projesi | Araştırmacı | TÜBİTAK 1001. SBAG 218S549 |
Mart 2016 | Mart 2016- Mart 2020 | Development of Novel Synthetic Agents for Prostate Cancer Treatment | Araştırma Projesi | Araştırmacı | TÜBİTAK-1003. 2015S009 |
Mart 2015 | Mart 2019 | Epigenetic Chemical Biology (EPICHEM) | Araştırma Projesi | Yürütücü | COST Action. (CM1406) |
Kasım 2013 | Kasım 2017 | Training in Neurodegeneration, Therapeutics Intervention & Neurorepair – TINTIN | Araştırma Projesi | Yürütücü | FP7. Marie Curie Initial Training Networks (ITN). Call: FP7-PEOPLE-2013-ITN. Project ID: 608381 |
Yayınlar
Title | Type | Publishing House | Year Released | Month | City | Journal Type |
---|---|---|---|---|---|---|
Synthesis, Anticancer Agents and Molecular Docking of (S)- Naproxen-1, 2, 4-Triazole Derivatives | Araştırma Makalesi | EMB | 2020 | 01 | Europe | European Journal of Medicinal Chemistry, 208.112841 |
Drug repurposing for coronavirus (COVID-19): In silico screening of known drugs against coronavirus 3CL hydrolase and protease enzymes | Araştırma Makalesi | Taylor and Francis | 2020 | 01 | ABD | Journal of Biomolecular Structure and Dynamics, 1-13. doi:10.1080/07391102.2020.1758791 |
New 2‐Pyrazoline and Hydrazone Derivatives as Potent and Selective Monoamine Oxidase A Inhibitors | Araştırma Makalesi | ACS | 2021 | 01 | ABD | Journal of Medicinal Chemistry |
Synthesis, Anticancer Activity on Prostate Cancer Cell Lines and Molecular Modeling Studies of Flurbiprofen-Thioether Derivatives as Potential Target of MetAP (type II). Medicinal Chemistry | Araştırma Makalesi | Bentham | 2020 | 01 | UK | Medicinal Chemistry, 16(6), 735-749, 2020. doi:10.2174/1573406415666190613162322 |
Identification of potential inhibitors of human methionine aminopeptidase (type II) for cancer therapy: Structure-based virtual screening, ADMET prediction and molecular dynamics studies. | Araştırma Makalesi | Elsevir | 2020 | 01 | ABD | Computational Biology and Chemistry, 86 doi:10.1016/j.compbiolchem. 2020.107244, (IF: 3.107). |